Two people are fighting for life after becoming trapped in a serious multi-vehicle crash which left three in hospital overnight.

Emergency services were called to Moggill Rd at Pinjarra Hills in Brisbane, just after 9.30pm on Monday, following reports of a six-vehicle crash.

Initial reports suggested up to six vehicles were involved, but police later confirmed three vehicles collided near Moggill Rd Service Rd.

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A 62-year-old man and a 60-year-old woman, both from Bellbowrie, were critically injured.

“A male patient in his 60s who was trapped in a vehicle was transported in a potentially life-threatening condition with chest and abdominal injuries,” Queensland Ambulance Service (QAS) said.

“A female patient in her 60s who was also trapped in the vehicle was transported in a potentially life-threatening condition with chest, abdominal and arm injuries.”

A third patient, a 23-year-old Chapel Hill man, was taken to hospital in a stable condition with minor injuries.

Queensland Police said investigations into the cause of the crash are ongoing.

Authorities are appealing for anyone with dashcam or CCTV footage to come forward.