A 37-year-old man has been slapped with dozens of charges over several alleged graffiti attacks at a Jewish house of worship.

The accused is alleged to have defaced the Melbourne Hebrew Congregation on Toorak Rd in South Yarra with “offensive graffiti” on six occasions.

The synagogue was targeted on March 11, June 21, June 22, July 22, and July 30, with the last attack taking place last week on August 19, according to police.

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Photos from one incident showed the words “Iran is da bomb” scrawled inside a mushroom cloud.

Police previously released security footage of a man they wanted to speak to over the vandalism.

At the time of the July incidents, a man was pictured concealing his identity with a Ghostface mask from the horror movie, Scream.

Police raided a South Yarra home on Monday morning, making an arrest and seizing items relating to the alleged crimes.

A 37-year-old was charged with six counts of criminal damage, six counts of marking offensive graffiti, five counts of using an unregistered motor vehicle, five counts of unlicensed, and driving one count of failing to stop on police direction.

He was bailed and will appear in Melbourne Magistrates’ Court on November 21.